The ANNOTICO Report

PREFACE:
This Procedure has fascinating implications, but my greatest concern is
that I read about SO many Medical and Scientific discoveries coming out of
Italy, that is equal to the best of Europe, and yet Italy is given little
Respect.

Italy's numerable successes  have been accomplished despite the grave
disadvantages of the (1)  'brain drain' (mostly to the USA), (2) and the
disadvantage Italian Universities put themselves at by their desire to
remain "pure" and not be contaminated by "associating" with Drug companies.

The lack of appropriate respect, is partially due to the Italians
reluctance to publish/translate their "papers" to English and submit for
publication in Recognized International Scientific Journals.

Even so, In the field of Oncology (Cancer): it's accepted that Italians are
in the forefront of Europeans, who are ahead of Americans. This is
especially true in the arena of  hemato-oncology (ditto, for malignancies
of the blood and lymphatic system: leukemias and lymphomas, plus the
anemias which, however, are not neoplastic in nature).

[*The last two paragraphs are wholly dependant on information provided by
Dr. Giorgio Iraci, a retired Chief of Neurosurgery at the University of
Perugia Hospital, (obviously in Umbria, Italy)]

Prof. Cesare Galli of the University of Bologna in Cremona, Italy; is
associated with the Laboratory of Reproductive Technology, and produced
this stallion, and also the predecessor, a filly, Prometea.

Pieraz-Cryozootech-Stallion, is named after his "sire" Pieraz, an Arabian
gelding that won the world endurance race championship in 1994 and 1996,
and Cryozootech (Cyro-Zoo-Tech, makes sense when you split it up), the
parent company of LRT.

Cryozootech has ambitious plans, and wants to clone more than thirty other
horses specialized in dressage or jumping. But it's not that simple. The
new foal was the only one which came alive, from 34 embryos implanted into
12 foster mothers.

The clone will be mature enough to breed within two years. But although the
new clone is Pieraz’s genetic twin, there is no guarantee that it will
perform as well as the champion racehorse. Environmental factors could be
crucial.Born on 25 February, weighing 42kg, he will not be used for
competition himself, but will instead make his living siring new
generations of horses.

New York Daily News
By Don Singleton
Staff Writer
April 16, 2005

Cloned foal, whom scientists (at the University of Bologna) in Cremona,
Italy, gave the rolls-off-the-tongue name of Pieraz-Cryozootech, is only
the second horse ever cloned and the first male.

Cryozootech (Cyro-Zoo-Tech, makes sense when you split it up) is the name
of the firm based in Sonchamp, near Paris.

After years of trying, scientists in Italy have cloned a stallion from a
sterile champion racehorse, raising the specter of armies of Secretariats
and Man o' Wars.

But don't look for such duplicates on tracks in the United States - clones
are barred from thoroughbred racing here.

The foal, born in February, is only the second horse clone ever born, and
the first male; the first one, a filly named Prometea, is now 2 years old.

The two equine clones were created at the laboratory of Prof. Cesare Galli
in Cremona, not far from Milan, the London Daily Telegraph reported
yesterday.

It was Galli who announced the birth of the foal, which is named
Pieraz-Cryozootech.

The foal's "sire" was Pieraz, an Arabian gelding that won the world
endurance race championship in 1994 and 1996 and currently lives in
retirement in Fort Valley, Va., at the stables of his owner, trainer and
rider, Valerie Kanavy.

Scientists in Galli's Laboratory of Reproductive Technology in Cremona
collected skin cells from Pieraz and transferred their DNA to egg cells
that had been emptied of their own genetic material. The resulting embryos
were then transferred into the wombs of surrogate mares, the Telegraph said.

"The original horse is a champion with a good record, but was gelded, so
couldn't have any offspring," Galli told the Telegraph.[Stallions are often
"gelded" at three years old to make the "higher spirited" stallions easier
to train]

"In these cases, the best horses are never bred, so they do not contribute
to genetic progress. What we have achieved overcomes this problem. In two
or three years, the cloned foal can be used as a stallion," Galli said.

Not likely, said Bob Curran, spokesman for the Jockey Club, the official
breed registry in North America.

"So far as we're concerned, it's a fantasy," Curran said yesterday. "The
Jockey Club would not register a cloned animal, nor a foal that resulted
from a cloned animal."

[Every thoroughbred in our registry is the descendant of two thoroughbreds,
so this concerns the integrity of the breed".

"If some scientist cloned a horse and wanted to raise the cloned horse in
their back yard that's fine, but that horse would not be registered by the
Jockey Club," Curran said.

RAA: That's Horse Pucky!!! The integrity can be upheld by DNA tests!!!!!!!]

http://www.nydailynews.com/front/
story/300536p-257163c.html